Danny Ings scored his 19th goal of the season but Southampton could not make their early dominance count in a 1-1 draw with Everton.
Bournemouth's hopes of avoiding relegation remain in the balance after Callum Wilson's last-gasp strike was ruled out by VAR for handball in their 0-0 draw with Tottenham.
Arsenal have failed in their attempts to get Eddie Nketiah's red card against Leicester overturned or his ban reduced.
Chelsea midfielder Billy Gilmour is expected to miss the rest of the season after suffering a knee injury.
The race for this season's Golden Boot remains wide open - so who is most likely to scoop the award?
Harry Kane and Riyad Mahrez's controversial disallowed goals for Tottenham and Manchester City last week would have been allowed under an amended handball law to be introduced next season.
Graham Potter insists Brighton can learn from their mistakes after being branded "naive in the extreme" by Graeme Souness for attempting to play out of defence during the defeat to Liverpool.
Premier League clubs have delayed a decision over the dates for this summer's transfer window.
Everton face a fight to sign Lille defender Gabriel Magalhaes after a second Premier League club made a late bid for the player.
FIFA has taken full operational control of Video Assistant Referees [VARs], world football's governing body has informed all associations.