Fernandes in for Yoro
Darren Fletcher makes just the one change to the Manchester United team picked by Ruben Amorim against Leeds but it is a significant one as captain Bruno Fernandes returns in place of Leny Yoro. That could signify a switch to a 4-2-3-1 formation.
Mason Mount, Harry Maguire and Kobbie Mainoo are among the substitutes.
Cunha to punish Burnley?
Manchester United’s Matheus Cunha has scored three goals in his last five Premier League appearances, as many as his previous 20 beforehand. Cunha has nine goal involvements (5 goals, 4 assists) in his last eight league games against newly promoted opponents.
Home horrors for Parker
Burnley’s Scott Parker has lost 65 per cent of his home Premier League matches as manager (24/37), the highest losing percentage of any manager to take charge of 25+ home games in Premier League history.
Man Utd set for back four?
Sky Sports' Adam Bate at Turf Moor:
"Dorgu joining in the shooting drills, Heaven and Martinez warming-up together. Does look like a return to a back four for United. Could this be the end of the Amorim experiment in more ways than one?"
Solskjaer? Conte?! Which managers fit Man Utd's 'DNA'?
Gary Neville has said the next Manchester United manager must suit the DNA of the club, so who fits the bill?
As their hierarchy begin talks with prospective candidates, Between the Lines returns with a look at how their options stack up.
Antonio Conte, Ole Gunnar Solskjaer among best fits for Man Utd 'DNA' after Ruben Amorim axe - Between the Lines
Sky Sports
Parker: We need a reaction
Burnley boss Scott Parker speaking to Sky Sports:
"We need a reaction. We fell short at the weekend.
"There’s no better team to face tonight."
Nev: Man Utd look stronger
Sky Sports' Gary Neville:
"All of a sudden there are a few players back on the bench and United look stronger. They should be doing a lot better. The results have been frustrating."
Last time out for Man Utd
Last time out for Burnley
'Ole loves the club'
Gary Neville shares his thoughts on who might take the interim head coach role until the end of the season at Manchester United.
Fletcher: It's up to players to execute our plan
Manchester United interim boss Darren Fletcher speaking to Sky Sports:
“We’re ready to go. I’m excited.
“It’s important Bruno is back. This game was targeted for a few of the players coming back from injury
“We’ve set them up in a way that we feel can win the match. It suits their personalities and styles. It’s up to them to execute it.”
Nev: Solskjaer return would be like Groundhog Day
Sky Sports' Gary Neville:
“They put Ryan [Giggs] in charge 10 years ago, then Ole came in charge and you go back to the old boys, then you go for a new one, then you go for more experience.
“It is almost like a cycle, like a movie we have all seen before and Groundhog Day.
“What I do think is Ole is someone who absolutely loves the club, he knows the job, he has been in the job.
“The other names that have been mentioned – Michael Carrick, Ruud van Nistelrooy – these are really fantastic people.
“I trained with those guys for a lot of years. They love the club intensely, they get the club, but still they are going to come under a lot of pressure in this next four or five months if results don’t go their way and they are going to have to be ready for that.
“Whoever is going to get it out of those three who are being mentioned, I wish them all the best because it is a tough role.”
Nev: An experienced interim crucial
Sky Sports' Gary Neville on Manchester United's search for an interim boss:
“They have to bring someone in who has done it before. I was put in a football club for four months and told to steer the ship to shore until the end of the season.
"Manchester United have had a challenging experience with Ralf Rangnick and it went well with Ole Gunnar Solksjaer. All I will say is as long as someone has done it before, got experience and can handle the media. The next full-time appointment is crucial.”
Esteve, Edwards & Hannibal all start
Sky Sports' Lewis Jones:
"Maxime Esteve returns for Burnley after limping off in the defeat to Newcastle. He is one of three changes from the defeat at Brighton as Marcus Edwards and Hannibal, only just back from AFCON, also return to the Burnley XI. Scott Park looks to be continuing with the 3-4-3 he's been playing in recent weeks."
Fernandes in for Yoro
Darren Fletcher makes just the one change to the Manchester United team picked by Ruben Amorim against Leeds but it is a significant one as captain Bruno Fernandes returns in place of Leny Yoro. That could signify a switch to a 4-2-3-1 formation.
Mason Mount, Harry Maguire and Kobbie Mainoo are among the substitutes.
Burnley team news
Team to play Man Utd: Dubravka, Walker, Esteve, Laurent, Humphreys, Pires, Florentino, Ugochukwu, Edwards, Hannibal, Broja
Subs: Weir, Hartman, Bruun Larsen, Foster, Anthony, Tchaouna, Ekdal, Sonne, Barnes
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Man Utd team news
Team to play Burnley: Lammens, Dalot, Heaven, Martinez, Shaw, Ugarte, Casemiro, Dorgu, Fernandes, Cunha, Sesko.
Subs: Bayindir, Maguire, Mainoo, Mount, Malacia, Yoro, J Fletcher, Lacey, Zirkzee.
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Team news in 60 seconds...!
What has this man got up his sleeve?
Jones Knows: Big Man Utd win on the cards
Sky Sports' betting expert Lewis Jones:
"Although Wolves are propping up the division, Burnley, according to the data, are actually the worst of the 20 teams.
"Their expected goals against numbers show them conceding 2.00 xG per 90, the worst figure in the division - that's a team consistently allowing opponents high-quality chances in dangerous areas. Burnley also sit bottom of the league for xG supremacy, posting a damaging -1.07 per 90. In simple terms, they're being comprehensively outplayed almost every week.
"Shot volume reinforces the same message. Burnley face more shots than any other Premier League team and concede more big chances than anyone else. This looks a fantastic opportunity for Manchester United's attackers to flex their muscles and the 7/4 with Sky Bet on them on the -1 handicap market looks an interesting angle to explore."
SCORE PREDICTION: 0-3
Fernandes, Mount, Mainoo & Maguire in Man Utd squad
Sky Sports News' Danyal Khan at Turf Moor:
"Bruno Fernandes, Mason Mount, Harry Maguire and Kobbie Mainoo all return from injury and are in the Manchester United squad."
Teams will be dropping at 7pm.
What's the latest in Manchester United's search for a new manager?
Latest from Sky Sports News' Rob Dorsett:
"Manchester United are working on a situation where they will bring in an interim manager until the end of the season and the reason they want to do that is because they think there is a much greater availability of talent they can get their hands on in the summer.
"Sky Sports News revealed on Tuesday that Ole Gunnar Solskjaer and Michael Carrick are both in the frame.
"I'm told Manchester United will continue talks with those two before they will make any further decision on an interim appointment.
"It has been made very, very clear to me that both of them could be employed together in some new role as part of that interim option.
"Jason Wilcox is leading this.
"Informal talks on Tuesday with both went very well on Tuesday. I've been told both Solskjaer and Michael Carrick would like to be involved in the first team at United again.
"There are no meetings planned today - it's a big day for Darren Fletcher today because he is leading the team tonight for the first time at Burnley. He doesn't want any distractions from that and all the focus is on the team.
"So I am expecting talks with to accelerate tomorrow and the end of the week.
"And then United have a decision to make."