Here’s all you need to know ahead of our clash with Michael Carrick’s side...
What time does the match start?
Kick-off is at 5.30pm BST on Saturday.
How can I watch the game?
Saturday’s match at Old Trafford will be televised live in the UK on Sky Sports Premier League and Sky Sports Main Event.
In addition, supporters can keep fully up-to-date with all the action via live text and audio commentary during the game on our Match Centre.
Video highlights will be posted on official club channels from two hours after the final whistle, while a full match replay will be available to watch on SPURSPLAY from midnight after the game.
What is the team news?
Roberto De Zerbi is set to speak to the media on Friday to clarify the latest team news coming out of the international break.
Who is the referee?
Stuart Attwell has been appointed referee for our game on Saturday.
Constantine Hatzidakis and Nick Hopton will be his assistants, with Rob Jones in place as the fourth official.
VAR will be handled by Jarred Gillett and assistant Stuart Burt.
Which kits will the teams be wearing?
Manchester United will be wearing their usual red shirts with white shorts and black socks.
We’ll be using our navy blue home shirts and shorts – the shirts featuring multicoloured patterns across the front – but will wear the white socks usually associated with our home kit, much like we did at Brentford on the opening day of the season.
United’s goalkeeper will be in yellow, with ours in green.
What will the weather be like?
The forecast is for light rain in Manchester on Saturday, with temperatures at around 12 degrees during the game.
What is the latest travel information?