We were drawn to face Spurs at the end of last month, with the last-eight tie representing our entry to the competition, having skipped the group stage due to our UEFA Women's Champions League participation.
Our opponents have reached this stage by topping Group E, coming out ahead of Aston Villa, Birmingham City and Bristol City.
It has now been confirmed that our League Cup tie against Spurs will be held at The Progress With Unity Stadium, formerly called Leigh Sports Village, at 13:00 GMT on Sunday 21 December.
Tickets to attend the game will available in due course, and it can also be streamed live on the Barclays WSL YouTube channel.
All four matches in this round will kick off simultaneously, with the same platform offering a multiview option.
The victors in our clash will then face the winners of Crystal Palace v Arsenal, to compete for a spot in the final.