Left-back Destiny Udogie is "progressing" in his recovery but is not yet available.
Midfielder Yves Bissouma will return to the squad after being left out of the Super Cup squad for persistent lateness. He added: "I have certain standards and demands and consequences if demands are not met."
He said the racist abuse Mathys Tel was subjected to after the Super Cup final "is terrible" and "no real Tottenham supporter" would do that.
More on Tel: "We're doing everything to support him in this situation. He's a strong person. We'll see the real Tottenham supporters at the stadium tomorrow backing him. In tough times we step up together. I expect really big cheers for him tomorrow."
Frank has been impressed by his players "very strong mentality" and their "ability to take on messages and gameplans" since taking over the role in June.
On whether he will have butterflies for the first home game in charge: "I will have tomorrow. If I'm honest, now I'm in work mode. I know when I wake up tomorrow and when I step into the stadium I will feel it."
Frank thought Richarlison was "really phenomenal" against Paris St-Germain because his "hold-up play, his intensity and his arriving in the box was top".
He said his players "have recovered well" from Wednesday's game but he can "freshen up" the squad if he chooses to.
The recruitment team "are working" to bring in more players before the transfer window closes and "will do something" if "they fit" into Frank's plans.
On the young players - like Mikey Moore, who has gone on loan to Rangers - and where they stand this season: "There is a fine balance. To train with professional, higher-level players and their intensity is very good, but the most important thing for any player is playing minutes. If I think it's the right time to get them out then I will."