'You paved the way'
An hour after the appointment of Frank was confirmed, Spurs captain Cristian Romero posted a message to his former boss Ange Postecoglou.
It included the line: "You paved the way despite the many obstacles that always existed and always will exist," which some supporters have viewed as a shot at Spurs chairman Daniel Levy, who chose to sack Postecoglou despite winning the Europa League.
'Frank is perfect match for Tottenham' - Eriksen
One player who has affiliations with both Tottenham and Brentford is Christian Eriksen.
The Denmark midfielder played for Spurs between 2013 and 2020 and also had a brief spell at the Bees under Thomas Frank in 2022.
With Eriksen now a free agent, he was recently asked about Frank and whether he would follow his compatriot to Spurs.
"I think he is the right coach for Tottenham,â Eriksen said.
"I think he is the perfect match for the club, and it would be great if Thomas takes on that challenge.
"His personality, his way of playing and his way of being. And the club considering where they were last season â they won a trophy of course â but they are in the process of building something up, and I am sure that Thomas is a good man to bring in."
The 33-year-old, however, added that he is yet to receive a call from Frank regarding a return to Spurs.
"No, not where we are now, so Thomas should call if something happens," he said.
'The time is now'
Phil McNulty
BBC Sport chief football writer
The time is now.
The Champions League awaits, and so does a mission to revive Spurs as a Premier League force.
What is clear is they have turned to a man whose career remains on an upwards curve.
Thomas Frank's playing career may have only taken in the Danish amateur game - he even spent time working in a kindergarten - but he progressed successfully as a coach through the Denmark national youth teams to Brondby, before joining Brentford as an assistant in 2016, then succeeding Dean Smith as head coach two years later when Smith moved to Aston Villa.
That enabled Frank to build the body of work that attracted admiring glances before Spurs and Levy were finally in the position to lure him from Brentford, where he was such a beloved figure and where supporters will be heartbroken, even if they had guessed this day would eventually come.
'One of the most progressive and innovative head coaches'
Tottenham Hotspur
Tottenham's statement in announcing the appointment of Thomas Frank noted the Dane's success at transforming Brentford into an established Premier League side:
"During his time at Brentford he [Thomas Frank] transformed the club, moving them up from the Championship to an established Premier League side, consistently and significantly outperforming expectations for an extended period of time.
"In Thomas we are appointing one of the most progressive and innovative head coaches within the game. He has a proven track record in player and squad development and we look forward to him leading the team as we prepare for the season ahead."
Frank's record at Brentford
Frank first joined Brentford as an assistant in 2016, before taking over from Dean Smith as head coach in October 2018.
In 2019-20 his side reached the Championship play-off final but suffered a 2-1 defeat by Fulham.
They reached the Championship play-off again the following season and beat Swansea City to reach the Premier League, with Frank becoming the first Brentford manager in 86 years to win promotion to the top flight.
Since then, Frank has established the Bees as a competitive Premier League club, recording 13th, ninth, 16th and 10th-place finishes.
Last season Brentford's tally of 66 goals in the Premier League was the joint fifth best in the division.
Of the 152 top-flight games Frank has overseen, he has won 54 and lost 60 - claiming 200 points from a possible 456.
Bees thank Frank for 'incredible impact'
Brentford
Since it was announced that Thomas Frank was in talks with Tottenham over the vacant manager's job, we have had a flood of messages from Brentford supporters wishing him well.
The powers-that-be at the Bees have responded in much the same way, releasing a statement following his appointment by Spurs to say that everyone connected with the club "would like to thank Thomas for the incredible impact he has had on the club's history".
Bees director of football Phil Giles said: "From the moment he replaced Dean Smith, he understood what we were trying to build and his wisdom, coaching ability and emotional intelligence have helped transform the club.
"But it's not just what you see on the pitch. He forged a special connection with our fans, helped develop and improve players, and was instrumental in implementing the culture that has seen Brentford go from strength to strength.
"We will never forget Thomas, but now it is time to thank him and take the next steps in our journey with a new leader who we believe can be just as successful and influential."
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Get Involved - Is Frank the right appointment?
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Tottenham have made a succession of false starts over the past six seasons following the departure in 2019 of Mauricio Pochettino, who had enjoyed five years in the hotseat.
Jose Mourinho, Nuno Espirito Santo, Antonio Conte and Ange Postecoglou have all tried and failed to take the club forward.
The question is: can Thomas Frank succeed where others have failed?
Give us a quick thumbs up if you believe he is the right appointment, thumbs down if you don't.
And please get in touch with your thoughts on why you either believe or don't believe Frank is the right choice.
Thanks.
Brentford's Frank replaces Postecoglou as Spurs manager
Thomas Frank has been appointed by Spurs as replacement for Ange Postecoglou, who was sacked following the end of last season despite guiding the club to a first trophy in 17 years.
Spurs beat Manchester United in the final of the Europa League to earn qualification for next season's Champions League.
But it was not enough to paper over the cracks that appeared following a 17th-place finish in the Premier League.
Spurs lost 22 of their 38 matches and finished seven places and 18 points below Brentford.
Justin Cochrane will join Frank at Tottenham as the Dane's assistant, despite efforts from the Bees to keep hold of the England coach.
Frank has also brought head of performance Chris Haslam and first-team analyst Joe Newton with him from Brentford, while another assistant coach, Andreas Georgson, arrives from Manchester United.