Following a quiet opening to the fixture at the Tottenham Hotspur Stadium, the hosts were soon reduced to 10 men when Xavi Simons received a red card for raking his studs down the back of Virgil van Dijk’s calf.
Spurs manager Thomas Frank took aim with the Video Assistant Referee’s (VAR) decision to upgrade Simons’ initial yellow card to a red after the full-time whistle, saying "the game is gone."
Liverpool were then incensed when Alexander Isak suffered a fractured leg following a challenge by Micky van de Ven after putting his side in front after 56 minutes.
Reds head coach Arne Slot later described Van de Ven’s tackle as "reckless", with Sweden striker Isak having subsequently been ruled out for a couple of months through injury.
And in what turned out to be an eventful evening for Spurs centre-back Romero, the 27-year-old received his first yellow card for dissent after remonstrating with referee John Brooks over what he perceived to be a foul on himself by Hugo Ekitike, who headed Liverpool into a two-goal lead.
While Tottenham showed great amounts of courage as they tried to get back into the game with ten players, they were soon reduced to nine when Romero was booked again for aiming a kick towards Liverpool’s Konate.
Former Atalanta and Juventus ace Romero protested angrily once again, before reluctantly heading down the tunnel as Spurs were left to wonder what might have been against Liverpool.
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And following his dismissal, Romero has now been charged by the FA, with Tottenham’s No. 17 having until Friday, 2 January to respond.
In a statement on Christmas Eve, English football’s governing body said: "Tottenham Hotspur’s Cristian Romero has been charged following their Premier League match against Liverpool on Saturday 20 December. It’s alleged that he acted in an improper manner by failing to promptly leave the field of play and/or behaving in a confrontational and/or aggressive manner towards the match referee after being sent off in the 93rd minute."