We look ahead to Saturday’s Premier League game at the Tottenham Hotspur Stadium with our Tottenham Hotspur vs Manchester United prediction and preview. Will United get revenge for the UEFA Europa League final?
Tottenham vs Manchester United: The Key Stats
The Opta supercomputer has declared Tottenham Hotspur as the favourites, with the London club winning 47.5% of its pre-match simulations.
Manchester United are winless in their last seven matches against Spurs.
Bruno Fernandes is looking to assist in a third consecutive away appearance for the first time since November 2020.
Tottenham and Manchester United have near-identical Premier League records this season. They have both won five and lost three of their 10 matches while scoring 17 goals. As Spurs have conceded half as many goals (eight versus 16) will that make the difference in this match?
It might if the game were being played at Old Trafford. Tottenham start the weekend at the top of the Premier League table for away matches while being 17th in the corresponding home standings.
Their poor form in north London extends beyond 2025-26, too. No side has lost more home Premier League matches in 2025 than Tottenham Hotspur (nine). Only in 1994 and 2003 (10 in each) have Spurs reached double figures for home defeats in a year in their league history.
While much of the current run rests with Ange Postecoglou, Thomas Frank has a poor record in front of his own fans, too. Across spells with Brentford and Spurs, the Dane has suffered nine defeats in his last 16 home Premier League matches, winning just three. Before this run, his Brentford side won seven of their previous eight home games, so he has overseen quite the dip.
Frank will hope both he and Tottenham hit rock bottom last weekend when it comes to bad performances on home turf. Spurs registered an xG of just 0.1 in their 1-0 defeat to Chelsea, the lowest by a team in a Premier League match so far this season. They are averaging just 9.7 shots per game in 2025-26, their lowest average in a Premier League campaign on record since 1997-98.
A much-improved midweek win over FC Copenhagen in the UEFA Champions League should improve confidence in the Spurs’ camp, but their cause in this match is not aided by two factors.
Firstly, they have the longest injury list in the Premier League at the time of writing, with 10 players out of action. Mohammed Kudus may be able to return, but Lucas Bergvall, Yves Bissouma, Dominic Solanke, Dejan Kulusevski and James Maddison are among the potential starters who will not be involved.
The other issue for Spurs is the potency of United’s attack. Only Liverpool (156) have had more shots in the Premier League this season than Manchester United (153) and no side has had more shots on target than they have (54).
His squad will be close to full strength here too, with Lisandro Martínez the only reported absentee for United. Two players who should be looking forward to this game are Bryan Mbeumo and Bruno Fernandes.
Only against Southampton and Brighton (five) has Mbeumo scored more Premier League goals than he has against Spurs, with three of his four against them coming at the Tottenham Hotspur Stadium. As for Fernandes, he has 53 Premier League assists – since his debut in February 2020, only Mohamed Salah (64) and Kevin De Bruyne (58) have more. He’s assisted in his last two away games and is looking to do so in three away appearances in a row for the first time since November 2020. Perhaps Mbeumo can help him achieve that?
Manchester United are unbeaten in their last four Premier League games (W3 D1), their joint best run under Amorim. They last had a longer run without losing in January/February 2024 (five games), which was also the last time they netted two or more goals in five in a row. But Tottenham completed the Premier League double over them last season and have a great recent record in this head-to-head. As such, it’s hard to know which way this game will go.
Tottenham vs Manchester United Head-to-Head
“Lads, it’s Tottenham.”
Sir Alex Ferguson’s famous line to his players that he used to downplay the threat of Spurs no longer applies. Manchester United are winless in their last seven meetings with Tottenham in all competitions, losing five, including each of the last four – the last team to win five in a row against the Red Devils were Liverpool between 2000 and 2002.
Spurs remarkably beat United four times last season alone, most notably in the UEFA Europa League final. They won 1-0 on home turf in the Premier League, also winning 4-3 at the Tottenham Hotspur Stadium in the Carabao Cup.
Tottenham vs Manchester United Prediction
The home side are favourites to win but not to the point that it is more likely than not.
The Opta supercomputer ran 10,000 simulations of the match, with Tottenham getting a victory in 47.5% of them. The other two potential outcomes have almost equal probabilities.
A Man Utd win (26.4%) has a slight edge over the chances of a draw (26.2%), though not by a significant amount. The visitors will need to overcome their recent history against Spurs and the supercomputer if they are to collect three points here.
Tottenham vs Manchester United Predicted Lineups
Tottenham Hotspur: Guglielmo Vicario, Pedro Porro, Kevin Danso, Micky van de Ven, Destiny Udogie, João Palhinha, Rodrigo Bentancur, Mohammed Kudus, Pape Matar Sarr, Wilson Odobert, Randal Kolo Muani.
Head coach: Thomas Frank
Manchester United: Senne Lammens, Leny Yoro, Matthijs de Ligt, Luke Shaw, Amad Diallo, Casemiro, Bruno Fernandes, Diogo Dalot, Bryan Mbeumo, Matheus Cunha, Benjamin Sesko.
Head coach: Ruben Amorim
Opta Power Rankings
The Opta Power Rankings are a global team ranking system. They assign an ability score to over 15,000 domestic football teams. This score is on a scale between zero and 100, where zero is the worst-ranked team in the world and 100 is the best team in the world.
Ahead of kick-off this weekend, here is the Opta Power Ranking for both sides.