Can Spurs continue to shine on home soil in the UEFA Champions League? We look ahead to Tuesday’s clash at the Tottenham Hotspur Stadium with our Tottenham vs Slavia Prague prediction and preview.
Tottenham vs Slavia Prague: The Key Stats
Tottenham are unbeaten in their last 22 UEFA club competition matches at home (W18 D4) and are the Opta supercomputer’s favourites to extend that with victory here (63%).
Spurs have avoided defeat in their last seven European matches against Czech opponents (W5 D2).
Slavia Prague are winless in their last 16 matches in the Champions League proper (D7 L9), and 12 without victory in major European competitions (D4 L10).
Tottenham and home comforts are two things that have not gone hand in hand in 2025, as far as the Premier League is concerned anyway.
Saturday’s 2-0 victory over Brentford – secured by first-half strikes from Richarlison and Xavi Simons – was just their fourth success in 17 home league games in 2025 (D3), during which they have registered 10 defeats, a joint-high for the club in a calendar year (also recording that tally in 1994 and 2003).
Yet, it has been a different story on the continent, with Thomas Frank’s side winning both their Champions League home games this season ahead of hosting Slavia Prague on Tuesday, scoring five goals without reply in beating Villarreal (1-0) and Copenhagen (4-0).
That has stretched the Europa League champions’ unbeaten streak in UEFA competition to 22 home matches (W18 D4), while they are now looking to register clean sheets in four successive European Cup/Champions League home games for the first time.
The omens are positive for Spurs, who are unbeaten in all four of their previous meetings with Slavia Prague (W3 D1) and have avoided defeat in their last seven matches against Czech opposition stretching back to 1962.
Despite coming out on the wrong end of an eight-goal thriller with Paris Saint-Germain last time out in the Champions League – suffering their first defeat in the league phase – Tottenham are just two points shy of the top eight in 16th place.
Standing in their way on Tuesday are a side still looking for their first European win of this term. Slavia are at least flying in the Czech First League, with a run of five straight wins moving them five points clear at the summit.
Their 3-0 defeat at home to Arsenal on Matchday 4 represents their only loss in 12 matches in all competitions. Jindrich Trpisovsky’s side have been unable to transfer their domestic form onto the European stage, though, occupying 31st place in the league phase with just three points on the board from five games.
Following their goalless draw with Athletic Club on MD5, Slavia are without a victory in their last 16 matches in the Champions League proper (D7 L9) since beating FCSB 2-1 in September 2007.
Slavia are also winless in their last 12 major European matches (D5 L7), and have won just two of their previous 16 games against English opposition (D4 L10).
They are looking to avoid becoming the first team not to score in five straight Champions League matches since Milan in October 2023, though their attack could be weakened by Tomás Chory’s potential absence through illness. However, Mojmír Chytil is likely to play, fresh from scoring braces in successive league games, including Friday’s 2-1 win over Teplice, while winger Ivan Schranz recently returned from injury.
Meanwhile, Spurs have Brennan Johnson available after suspension following his red card against Copenhagen. Destiny Udogie was a late withdrawal ahead of Spurs’ win over Brentford, so the left-back is unlikely to be risked here. Randal Kolo Muani was seen limping after the weekend win and is a doubt.
Tottenham vs Slavia Prague Head-to-Head
Tottenham are unbeaten in their four previous meetings with Slavia Prague in UEFA club competitions (W3 D1), all of which were played in the UEFA Cup between 2006 and 2008.
Spurs have also avoided defeat in each of their last seven matches against Czech opponents (W5 D2), since a 1-0 reverse against Dukla Prague in the first leg of their European Cup quarter-final tie in February 1962.
Meanwhile, Slavia have won only two of their 16 previous European games against English teams (D4 L10). Both of those victories came in the UEFA Cup/Europa League, beating Leeds United 2-1 in 2000 and Leicester City in 2021.
Tottenham vs Slavia Prague Prediction
The Opta supercomputer favours a home win, with Tottenham victorious in 63% of their 10,000 pre-match simulations.
Slavia Prague’s chances of claiming victory are rated at just 17%, with a draw at 20%.
Tottenham vs Slavia Prague Predicted Lineups
Tottenham: Guglielmo Vicario, Pedro Porro, Cristian Romero, Micky van de Ven, Djed Spence, Rodrigo Bentancur, Pape Sarr, Lucas Bergvall, Mohammed Kudus, Brennan Johnson, Richarlison.
Head coach: Thomas Frank
Slavia Prague: Jindrich Stanek, Tomás Holes, David Zima, Stepán Chaloupek, Christos Zafeiris, Michal Sadílek, David Doudera, Jan Boril, Mojmír Chytil, Lukás Provod, Erik Prekop.
Head coach: Jindrich Trpisovsky
Opta Power Rankings
The Opta Power Rankings are a global team ranking system. They assign an ability score to over 10,000 domestic football teams. This score is on a scale between zero and 100, where zero is the worst-ranked team in the world and 100 is the best team in the world.
Ahead of kick-off on Tuesday, here is the Opta Power Ranking for both sides.