West Ham make one change to the side that won 3-0 in the Premier League at Nottingham Forest before the international break with Crysencio Summerville coming in for Niclas Fullkrug.
West Ham XI: Hermansen, Diouf, Kilman, Mavropanos, Walker-Peters, Ward-Prowse, Soucek, Fernandes, Paqueta, Bowen, Summerville.
Subs: Areola, Julio, Wilson, Fullkrug, Guilherme, Magassa, Wan-Bissaka, Potts, Irving.
Tottenham hand Xavi Simons a debut as one of three changes from the side that started their 1-0 loss to Bournemouth in the Premier League before the September international matches.
Mathys Tel and Lucas Bergvall also start with Rodrigo Bentancur, Richarlison and Brennan Johnson on the bench along with deadline-day signing Randal Kolo Muani.
Tottenham XI: Vicario, Spence, Van de Ven, Romero, Porro, Sarr, Palhinha, Bergvall Simons, Tel, Kudus.