It is one of the biggest fixtures in the Premier League calendar on Sunday as Arsenal play host to Tottenham Hotspur in the first North London Derby of the season.
The North London Derby is always one of the most highly anticipated matches in the campaign, with Gary Neville describing it as "one of his favourite games" in the calendar.
Arsenal sit proudly at the top of the Premier League table going into the contest, knowing that, after results on Saturday, they can open up a six-point lead at the top of the table with victory over their fierce rivals.
Spurs, meanwhile, are eighth, but can move up into fourth with victory. That will be no mean feat, however, with the Lilywhites having not won on Arsenal soil since 2010.
The fixture will be missing some key players, with as many as 20 potentially out of action. Here GIVEMESPORT takes a look at the latest team news and give our predicted teams for the massive clash.
Arsenal team news
Arsenal will be without influential centre-back Gabriel Magalhaes for the visit of Spurs, after the defender picked up a knock on international duty with Brazil. Mikel Arteta confirmed in his pre-match press conference that the defender will be out for "weeks".
He said: "Gabriel unfortunately picked up an injury with the Brazilian national team and he's going to be out for weeks."
Riccardo Calafiori missed joining up with Italy during the international break and he is also a doubt for the clash, with Arteta saying: "He's been carrying a few things, and we have to bring him back, and he hasn't trained yet, so tomorrow we have another training session and see how he is."
Kai Havertz, Gabriel Jesus, Martin Odegaard and Noni Madueke are all closing in on a return to action, but this may come too soon for all of them. Viktor Gyokeres is set to miss the match too, while there are also doubts over Gabriel Martinelli.
It means Arteta does not have too much to choose from when it comes to naming his side for the big match.
Arsenal predicted team: Raya; Timber, Mosquera, Saliba, Lewis-Skelly; Zubimendi, Rice, Eze; Saka, Merino, Trossard.
Tottenham team news
Thomas Frank had a number of injury issues himself, heading into the match, but he gave a positive update on many of those concerns in his pre-match press conference.
Pape Matar Sarr picked up a knock on international duty and it was feared he could miss the match across north London. There were also concerns over Lucas Bergvall, Mohammed Kudus and Randal Kolo Muani, but it seems all are ready to play again.
Frank said: "They are good, most of them. Pape trained today. He's ready, available. Lucas trained today. Ready, available. Kolo Muani, yes. Trained today. Available, of course has a mask [he] needs to play with. He [Kudus] trained today as well, so that is good."
Frank also delivered an updated on Ben Davies, Archie Gray and Kota Takai, saying the trio have also trained with the team and are back in contention.
That means that James Maddison, Dejan Kulusevski, Radu Dragusin and Dominic Solanke remain the only ones on the sidelines currently.