Last Word on Football brings you the latest team news and predicted lineups ahead of Brentford vs Tottenham Hotspur in Gameweek 1 of the 2026/27 Premier League season. Spurs begin their first full campaign under Roberto De Zerbi looking to put back-to-back 17th-place finishes behind them.
Tottenham have invested heavily during the summer transfer window, making six new signings to date, with several of those new arrivals in line to make their competitive debuts at the Gtech Community Stadium.
Brentford enjoyed a more successful 2025/26 campaign, finishing ninth under Keith Andrews and matching their highest Premier League finish. The Bees have also added to their ranks this summer and will be hoping to get off to a positive start on home soil.
Here is the latest team news for Brentford vs Tottenham.
Brentford vs Tottenham: Team News for Premier League Opener
Date: Saturday 22nd August 2026
Venue: Gtech Community Stadium
Kick-off: 17:30 BST
Last meeting: Brentford 0-0 Tottenham (1st January 2026, Premier League)
Referee: Michael Oliver
Current odds: Brentford 6/4, Tottenham 15/8, Draw 11/4
Brentford Team News
Brentford will be without Sepp van den Berg for the opening part of the season with a groin issue, meaning Kristoffer Ajer and Nathan Collins are expected to partner one another at the heart of the defence.
The Bees will also be without Antoni Milambo, who remains sidelined after suffering a serious knee injury last season. Otherwise, Andrews appears to have a fully fit squad to choose from ahead of the season opener.
Brentford have made four signings so far this summer, breaking their transfer record to sign Mamadou Sangare from Lens, while also adding Jaidon Anthony, Callum Wilson and Jannik Schuster to their ranks.
All four could make their competitive debuts in this one, although Sangare looks the most likely to feature from the start in midfield.
The Bees enjoyed an impressive end to pre-season, including a 7-0 victory over Eintracht Frankfurt, and will be hoping that form carries into the opening weekend of the Premier League campaign.
Read More: How Kinsky Became Tottenham Number 1 Just Months After Horror Night
Tottenham Team News
Tottenham have made significant changes to their squad during the summer, with Jan Paul van Hecke, Marcos Senesi, Andy Robertson and Sandro Tonali all in line to make their competitive debuts for the club.
Mateus Fernandes has also been declared fit by De Zerbi, although his game time during pre-season was limited after he suffered a minor issue. The Italian has also confirmed that James Maddison, Destiny Udogie and Dominic Solanke are available despite the trio missing most of pre-season.
Spurs will be without newly appointed captain Micky van de Ven and vice-captain Pedro Porro for this one, while Pape Matar Sarr has also been ruled out with a hamstring issue.
Tottenham will also be without Mohammed Kudus, Wilson Odobert, Xavi Simons and Dejan Kulusevski, all of whom continue their recovery from long-term injuries. Kudus is the closest of the quartet to returning to action.
Read More: Roberto De Zerbi Delivers Injury Update on Tottenham Star
Their absences could open the door to a start for Mikey Moore, who scored twice in Spurs’ 3-0 win over Hoffenheim in north London last weekend.
De Zerbi’s side went unbeaten during pre-season and will be hoping to carry that momentum into their opening game of the 2026/27 campaign.
Brentford Predicted Lineup
Kelleher, Kayode, Ajer, Collins, Lewis-Potter, Sangare, Janelt, Jensen, Ouattara, Schade, Igor Thiago
Tottenham Predicted Lineup
Kinsky, Gray, Van Hecke, Senesi, Robertson, Tonali, Fernandes, Gallagher, Moore, Tel, Richarlison
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