But the Italian will have a very different off-field team to that which backed him at the Seagulls.
Notably, Andrea Maldera is not a part of the line-up revealed by Spurs ahead of De Zerbi’s first match in charge.
Marcattilio Marcattilii, who worked with his compatriot at Albion, has been named first team fitness coach.
And Marcello Quinto has been appointed senior professional development phase coach.
Maldera was widely expected to be a part of the new set-up.
He was a valued sidekick of De Zerbi at previous clubs, including Marseille, and stepped in as head coach at the Tottenham Hotspur Stadium when his boss was suspended for a fixture two years ago.
Nor is there a role for Enrico Venturelli, who was a familiar sight at De Zerbi’s press conferences at Albion as he helped with translation.
Bruno was one of six members of staff who left the Seagulls early in the 2022-23 season bound for Chelsea, leaving the stage for De Zerbi and his sizeable staff to take over.
De Zerbi’s first training sessions appear to have caused a positive reaction among those who follow Spurs closely.
His side head to Sunderland at the weekend before hosting Albion a week on Saturday.