The promotion-winning captain is part of Igor Tudor’s coaching set-up at Tottenham Hotspur.
He was previously on the staff at Chelsea and West Ham in support of Graham Potter following their move from the Amex in 2022.
Bruno becomes assistant coach for Tudor, who is in charge at Spurs until the end of the season as successor to the sacked Thomas Frank.
He will add valuable Prem insight and has been appointed along with goalkeeping coach Tomislav Rogic and conditioning expert Riccardo Ragnacci, to join five existing members of staff.
The new-look set-up go in at the deep end with a first game at home to arch rivals and Premier League leaders Arsenal on Sunday.
Bruno made 235 appearances across seven seasons for the Seagulls after joining from Valencia in 2012, retiring at the end of the 2018-19 season.
He immediately headed to Belfast to take an end-of-season UEFA coaching course and was later appointed to Potter’s staff.
Many Albion fans were angered by his decision to follow Potter to Chelsea as six members of staff in total made the switch a few weeks into the 2022-23 campaign.
They included Bjorn Hamberg, who this week left his post as head coach of Albion under-18s to become senior head coach at Elfsborg in Sweden.