UEFA Nations League action is high on the agenda for many, while there are also Africa Cup of Nations and European Under-21 Championship qualifiers coming up.
A number of our summer signings are in line to win their first international caps as Spurs players, while Antonin Kinsky returns to the senior Czech Republic squad for the first time since 2024.
On-loan Yang Min-Hyeok, meanwhile, is currently away representing South Korea Under-23s at the Asian Games in Japan.
Here’s a run-down of when and where our players will be playing over the course of this international window (all kick-off times are UK)...
Tuesday 22 September
Yang Min-Hyeok – South Korea Under-23s Asian Games group stage match against Saudi Arabia – kick-off 11am
Wednesday 23 September
Mikel Jack, George Jobling, Kwasi Senyah and Toju Wellspring – England Under-17s home friendly against Republic of Ireland – kick-off 6.30pm
Thursday 24 September
Rodrigo Bentancur – Uruguay away friendly against Japan – kick-off 11.05am
Phoenix Offiah and Oscar Sandiford – England Under-18s tournament match against Colombia in Switzerland – kick-off 5pm
Ben Davies – Wales away UEFA Nations League match against Portugal – kick-off 7.45pm
Micky van de Ven and Jan Paul van Hecke – Netherlands home UEFA Nations League match against Germany – kick-off 7.45pm
Kevin Danso – Austria home UEFA Nations League match against Israel – kick-off 7.45pm
Friday 25 September
Mikey Moore – England Under-20s Euro Elite League match against Italy in Spain – kick-off 10.30am
Mathys Tel – France Under-21s away European Under-21 Championship qualifier against Iceland – kick-off 4pm
Mateus Fernandes – Portugal Under-21s away European Under-21 Championship qualifier against Bulgaria – kick-off 4.30pm
Jamie Donley – Northern Ireland away UEFA Nations League match against Georgia – kick-off 5pm
Malachi Hardy and Luca Williams-Barnett – England Under-19s home friendly against Republic of Ireland – kick-off 7pm
Archie Gray – England Under-21s home European Under-21 Championship qualifier against Kazakhstan – kick-off 7.30pm
Lucas Bergvall / Radu Dragusin – Sweden home UEFA Nations League match against Romania – kick-off 7.45pm
Sandro Tonali and Guglielmo Vicario – Italy home UEFA Nations League match against Belgium – kick-off 7.45pm
Omar Marmoush – Egypt home Africa Cup of Nations qualifier against Angola – kick-off 8pm
Pape Matar Sarr – Senegal home Africa Cup of Nations qualifier against Mozambique – kick-off 8pm
Saturday 26 September
Andy Robertson – Scotland away UEFA Nations League match against Slovenia – kick-off 2pm
Martin Dubravka – Slovakia home UEFA Nations League match against Moldova – kick-off 7.45pm
Antonin Kinsky – Czech Republic home UEFA Nations League match against Croatia – kick-off 7.45pm
Sunday 27 September
Phoenix Offiah and Oscar Sandiford – England Under-18s tournament match against Egypt in Switzerland – kick-off 2pm
Ben Davies – Wales away UEFA Nations League match against Denmark – kick-off 5pm
Micky van de Ven and Jan Paul van Hecke – Netherlands away UEFA Nations League match against Serbia – kick-off 5pm
Kevin Danso – Austria home UEFA Nations League match against Kosovo – kick-off 5pm
Monday 28 September
Rodrigo Bentancur – Uruguay away friendly against South Korea – kick-off 12pm
Mikel Jack, George Jobling, Kwasi Senyah and Toju Wellspring – England Under-17s tournament match against Israel in Germany – kick-off 3pm
Lucas Bergvall – Sweden home UEFA Nations League match against Poland – kick-off 7.45pm
Sandro Tonali and Guglielmo Vicario – Italy away UEFA Nations League match against Turkey – kick-off 7.45pm
Jamie Donley – Northern Ireland home UEFA Nations League match against Hungary – kick-off 7.45pm
Radu Dragusin – Romania home UEFA Nations League match against Bosnia-Herzegovina – kick-off 7.45pm
Tuesday 29 September
Mikey Moore – England Under-20s Euro Elite League match against France in Spain – kick-off 10.30am
Omar Marmoush – Egypt away Africa Cup of Nations qualifier against South Sudan – kick-off 2pm
Pape Matar Sarr – Senegal away Africa Cup of Nations qualifier against Ethiopia – kick-off 2pm
Malachi Hardy and Luca Williams-Barnett – England Under-19s friendly against Norway in Spain – kick-off 3pm
Mathys Tel – France Under-21s away European Under-21 Championship qualifier against Estonia – kick-off 5pm
Martin Dubravka – Slovakia home UEFA Nations League match against Kazakhstan – kick-off 7.45pm
Antonin Kinsky – Czech Republic home UEFA Nations League match against England – kick-off 7.45pm
Andy Robertson – Scotland home UEFA Nations League match against Switzerland – kick-off 7.45pm
Wednesday 30 September
Phoenix Offiah and Oscar Sandiford – England Under-18s tournament match against South Korea in Switzerland – kick-off 10am
Armend Muslika – Albania Under-19s home friendly against Lithuania – kick-off 3.30pm
Mateus Fernandes – Portugal Under-21s home European Under-21 Championship qualifier against Gibraltar – kick-off 8pm
Thursday 1 October
Mikel Jack, George Jobling, Kwasi Senyah and Toju Wellspring – England Under-17s tournament match against Venezuela in Germany – kick-off 10.30am
Ben Davies – Wales home UEFA Nations League match against Norway – kick-off 7.45pm
Micky van de Ven and Jan Paul van Hecke – Netherlands away UEFA Nations League match against Greece – kick-off 7.45pm
Kevin Danso – Austria away UEFA Nations League match against Republic of Ireland – kick-off 7.45pm
Friday 2 October
Armend Muslika – Albania Under-19s home friendly against Lithuania – kick-off 3.30pm
Malachi Hardy and Luca Williams-Barnett – England Under-19s friendly against USA in Spain – kick-off 3pm
Lucas Bergvall – Sweden away UEFA Nations League match against Bosnia-Herzegovina – kick-off 7.45pm
Martin Dubravka – Slovakia away UEFA Nations League match against Faroe Islands – kick-off 7.45pm
Jamie Donley – Northern Ireland UEFA Nations League match against Ukraine in Slovakia – kick-off 7.45pm
Archie Gray – England Under-21s home European Under-21 Championship qualifier against Slovakia – kick-off 7.45pm
Sandro Tonali and Guglielmo Vicario – Italy away UEFA Nations League match against France – kick-off 7.45pm
Radu Dragusin – Romania away UEFA Nations League match against Poland – kick-off 7.45pm
Saturday 3 October
Oliver Salter – Wales Under-18s away friendly against Finland – kick-off 11am
Mikey Moore – England Under-20s Euro Elite League match against Germany in Spain – kick-off 4.30pm
Mathys Tel – France Under-21s home European Under-21 Championship qualifier against Luxembourg – kick-off 6pm
Antonin Kinsky – Czech Republic away UEFA Nations League match against Spain – kick-off 7.45pm
Andy Robertson – Scotland away UEFA Nations League match against North Macedonia – kick-off 7.45pm
Phoenix Offiah and Oscar Sandiford – England Under-18s tournament match in Switzerland – opponents and kick-off time TBC
Sunday 4 October
Mikel Jack, George Jobling, Kwasi Senyah and Toju Wellspring – England Under-17s tournament match against Germany in Germany – kick-off 10.30am
Pape Matar Sarr – Senegal friendly against Comoros in France – kick-off 1pm
Kevin Danso – Austria away UEFA Nations League match against Kosovo – kick-off 5pm
Omar Marmoush – Egypt home friendly against South Africa – kick-off 7pm
Ben Davies – Wales home UEFA Nations League match against Denmark – kick-off 7.45pm
Micky van de Ven and Jan Paul van Hecke – Netherlands home UEFA Nations League match against Serbia – kick-off 7.45pm
Monday 5 October
Oliver Salter – Wales Under-18s away friendly against Finland – kick-off 10am
Malachi Hardy and Luca Williams-Barnett – England Under-19s friendly against Belgium in Spain – kick-off 12pm
Radu Dragusin / Lucas Bergvall – Romania home UEFA Nations League match against Sweden – kick-off 7.45pm
Sandro Tonali and Guglielmo Vicario – Italy home UEFA Nations League match against Turkey – kick-off 7.45pm
Jamie Donley – Northern Ireland home UEFA Nations League match against Georgia – kick-off 7.45pm
Tuesday 6 October