The North London derby will be one of four matches that Cristian Romero will miss for Tottenham after picking up his second red card of the season against Manchester United
They lost at Manchester United in Saturday's early kick-off, a result in no small part due to captain Cristian Romero's reckless first-half red card.
It left them level on points with Leeds United, who impressively beat fellow relegation battlers Nottingham Forest 3-1 on Friday night.
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Another Tottenham transfer window closes, and it will be interesting to see who in the fan base is still supporting the ENIC regime. There was a time when certain supporters defended the shrewd spending of our Lords and masters.
It turned out to be another exciting weekend in the Premier League at both the top and bottom ends of the table
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A huge Leeds United boost has been followed by mixed fortunes for key rivals - and the bookies have now produced their new predicted final Premier League table.
Tottenham Hotspur opens the upcoming Premier League round, 26 out of 38, with a duel against Newcastle on Tuesday at 19:30 GMT, 20:30 CET. And they are in a precarious situation: 15th in the table with 29 points, same points as Leeds United, only three spots above relegation.
Goals on either side of the half-time interval from Keira Walsh and Alyssa Thompson, coupled with a solid defensive display to keep the clean sheet, ensured Chelsea claimed a much-needed victory in the WSL.