Spurs conclude the Premier League campaign at home to the Seagulls, though there has been question raised over how strong a team Postecoglou can name following events this week.
After beating Manchester United in the Europa League final on Wednesday night, the players celebrated with supporters on Friday during a trophy parade through the streets of north London.
He said: “I really feel you need to celebrate your achievements properly and that was kind of my message to the boys.It’s important to make the experience as memorable as possible so that when I ask them to climb the mountain again, there’s a reason for it.
“It’s fair to say they’ve certainly enjoyed themselves over the last couple of days but the boys are all good, we’ll be good tomorrow.”
With that said, Yves Bissouma is a doubt while captain Heung-min Son and Cristian Romero will miss out along with Dejan Kulusevski, James Maddison, Lucas Bergvall and Radu Dragusin.
Postecoglou added: “There will be a couple of absences. Romero has been struggling with his toe for quite a while so we’ll leave him out, probably Sonny as well because his foot has still not healed.
“They both made a massive effort to get to the final. Bissouma got a knock in the game so he’s 50/50 at the moment but the rest of them physically are okay.”
Antonin Kinsky could make his third straight start in the Premier League, whilst the likes of Djed Spence, Archie Gray, Ben Davies, Mikey Moore, Wilson Odobert and Mathys Tel are all pushing for recalls.