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Spence adds to Spurs’ growing injury list, with centre-backs Micky van de Ven and Kevin Danso also not involved against City.

Tottenham Hotspur welcome champions Manchester City in what could be a massive game in the Premier League title race, and you can follow it all live with ESPN.

Here's the Tottenham team that Thomas Frank has selected to face Manchester City in the Premier League on Sunday evening

Thomas Frank has made four changes to his Tottenham team to face Manchester City on Sunday in the Premier League from his remaining fit and available players.

Tottenham have been handed another fresh injury blow with Djed Spence missing from their squad to face Manchester City. The versatile defender played the full 90 minutes of the Champions League win over Eintracht Frankfurt, but is missing from the weekend's squad.

We can now confirm the starting XI and substitutes for our Premier League encounter Manchester City on Sunday.

Thomas Frank has made four changes to the side which started our 2-0 win at Eintracht Frankfurt in the UEFA Champions League in midweek.